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TargetAngiotensin II type 1a (AT-1a) receptor
LigandBDBM50280332
Substrate/Competitorn/a
Meas. Tech.ChEBML_36160
IC50 3100±n/a nM
Citation Murray WVLalan PGill AAddo MFLewis JMLee DKRampulla RWachter MPHsi JDUnderwood DC Substituted piperidin-2-one biphenyltetrazoles as angiotensin II antagonists Bioorg Med Chem Lett 2:1775-1779 (1992)    Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II type 1a (AT-1a) receptor
Name:Angiotensin II type 1a (AT-1a) receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41107.81
Organism:Bos taurus
Description:ChEMBL_36779
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVC
AFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFK
IILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50280332
n/a
NameBDBM50280332
Synonyms:4,4-Diethyl-6-[2-oxo-prop-(E)-ylidene]-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-piperidin-2-one | CHEMBL52046
TypeSmall organic molecule
Emp. Form.C26H29N5O2
Mol. Mass.443.5408
SMILESCCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(C1)=CC(C)=O |w:29.33|
Structure
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