| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50280521 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_138398 |
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| Kd | 9700±n/a nM |
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| Citation |  Kozikowski, AP; Fauq, AH; Miller, JH; McKinney, M Alzheimer's therapy: an approach to novel muscarinic ligands based upon the naturally occurring alkaloid himbacine. Bioorg Med Chem Lett2:797-802 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
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| Type: | Protein |
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| Mol. Mass.: | 51442.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11229 |
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| Residue: | 460 |
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| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50280521 |
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| n/a |
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| Name | BDBM50280521 |
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| Synonyms: | (4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-2-yl)-allyl]-dihydro-furan-2-one | CHEMBL22923 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H23NO2 |
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| Mol. Mass. | 237.3379 |
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| SMILES | C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C |
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| Structure | 
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