| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50009291 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_140043 |
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| IC50 | 4460±n/a nM |
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| Citation |  Sanders, KB; Thomas, AJ; Pavia, MR; Davis, RE; Coughenour, LL; Myers, SL; Fisher, S; Moos, WH Cholinergic agents: aldehyde, ketone, and oxime analogues of the muscarinic agonist UH5 Bioorg Med Chem Lett2:803-808 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51555.53 |
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| Organism: | RAT |
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| Description: | P10980 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRI
VKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50009291 |
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| n/a |
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| Name | BDBM50009291 |
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| Synonyms: | CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-methyl-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C9H16N2O |
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| Mol. Mass. | 168.2361 |
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| SMILES | CN(C)CC#CCN(C)C(C)=O |
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| Structure | 
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