Reaction Details | |||
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Target | Acetylcholinesterase | ||
Ligand | BDBM50060470 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_27996 | ||
IC50 | 12±n/a nM | ||
Citation | Gregor, VE; Emmerling, MR; Lee, C; Moore, CJ The synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory activity of tacrine (Cognex®) derivaties Bioorg Med Chem Lett2:861-864 (1992) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Acetylcholinesterase | |||
Name: | Acetylcholinesterase | ||
Synonyms: | ACES_ELEEL | Acetylcholinesterase (AChE) | Acetylcholinesterase (EeAChE) | ache | ||
Type: | Enzyme | ||
Mol. Mass.: | 71812.79 | ||
Organism: | Electrophorus electricus (Electric eel) | ||
Description: | n/a | ||
Residue: | 633 | ||
Sequence: |
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BDBM50060470 | |||
n/a | |||
Name | BDBM50060470 | ||
Synonyms: | 10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6,8,10-pentaen-3-amine | 10-azoniatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6,8,10-pentaen-3-amine | 3-azatetracyclo[10.2.1.0^{2,11}.0^{4,9}]pentadeca-2(11),3,5,7,9-pentaen-10-amine | 9-Amino-1,4-methano-1,2,3,4-tetrahydroacridine | CHEMBL431844 | ||
Type | Small organic molecule | ||
Emp. Form. | C14H14N2 | ||
Mol. Mass. | 210.2744 | ||
SMILES | Nc1c2C3CCC(C3)c2nc2ccccc12 | ||
Structure |