| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50281497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201269 |
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| Ki | 1.75±n/a nM |
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| Citation |  Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG 4-Aryltetrahydropyridines as selective σ ligands Bioorg Med Chem Lett3:277-280 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50281497 |
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| n/a |
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| Name | BDBM50281497 |
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| Synonyms: | 4-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-pyridine | CHEMBL421195 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23FN2 |
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| Mol. Mass. | 310.4084 |
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| SMILES | Fc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1 |t:8| |
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| Structure | 
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