| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50281661 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_145964 |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Higginbottom, M; Nolan, W; O'Toole, J; Ratcliffe, GS; Rees, DC; Roberts, E The design and synthesis of kappa opioid ligands based on a binding model for kappa agonists Bioorg Med Chem Lett3:841-846 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42648.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41145 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
|
|
|---|
| BDBM50281661 |
|---|
| n/a |
|---|
| Name | BDBM50281661 |
|---|
| Synonyms: | 2-Oxa-7,10-diaza-bicyclo[11.3.1]heptadeca-1(17),13,15-trien-11-one | CHEMBL353264 | PD-146884 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H20N2O2 |
|---|
| Mol. Mass. | 248.3208 |
|---|
| SMILES | O=C1Cc2cccc(OCCCCNCCN1)c2 |
|---|
| Structure | 
|
|---|
Search and Browse
