| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
|---|
| Ligand | BDBM50281778 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_144150 |
|---|
| IC50 | 16±n/a nM |
|---|
| Citation |  Beck-Sickinger, AG; Hoffmann, E; Gaida, W; Grouzmann, E; Dürr, H; Jung, G Novel Y2-selective, reduced-size agonists of neuropeptide Y Bioorg Med Chem Lett3:937-942 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 2 |
|---|
| Name: | Neuropeptide Y receptor type 2 |
|---|
| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42734.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
|
|
|
|---|
| BDBM50281778 |
|---|
| n/a |
|---|
| Name | BDBM50281778 |
|---|
| Synonyms: | Ac-RHYIN-(Cha)-ITRQRY | CHEMBL415176 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C77H121N25O19 |
|---|
| Mol. Mass. | 1700.9407 |
|---|
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
