| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
|---|
| Ligand | BDBM50281873 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_98514 (CHEMBL706536) |
|---|
| IC50 | 40±n/a nM |
|---|
| Citation |  Sofia, MJ; Floreancig, P; Jackson, WT; Marder, P; Saussy, DL; Silbaugh, SA; Cockerham, SL; Froelich, LL; Roman, CR; Stengel, PW; Fleisch, JH Acid unit modifications of 1,2,4,5-substituted hydroxyacetophenones and the effect on in vitro and in vivo LTB4 receptor antagonism Bioorg Med Chem Lett3:1147-1152 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Leukotriene B4 receptor 1 |
|---|
| Name: | Leukotriene B4 receptor 1 |
|---|
| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 37582.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q15722 |
|---|
| Residue: | 352 |
|---|
| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
|
|
|
|---|
| BDBM50281873 |
|---|
| n/a |
|---|
| Name | BDBM50281873 |
|---|
| Synonyms: | CHEMBL15559 | Sodium; 7-[3-(4-acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H31O7 |
|---|
| Mol. Mass. | 455.5207 |
|---|
| SMILES | CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)ccc2CCC(Oc12)C([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
