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Reaction Details
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TargetLeukotriene B4 receptor
LigandBDBM81519
Substrate/Competitorn/a
Meas. Tech.ChEMBL_98504
Ki 78±n/a nM
Citation Sofia MJFloreancig PJackson WTMarder PSaussy DLSilbaugh SACockerham SLFroelich LLRoman CRStengel PWFleisch JH Acid unit modifications of 1,2,4,5-substituted hydroxyacetophenones and the effect on in vitro and in vivo LTB4 receptor antagonism Bioorg Med Chem Lett 3:1147-1152 (1993)    Article
More Info.:Get all data from this article,  Assay Method
 
Leukotriene B4 receptor
Name:Leukotriene B4 receptor
Synonyms:Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | LTB4-R 1 | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2Y purinoceptor 7 | P2Y7
Type:Enzyme Catalytic Domain
Mol. Mass.:37582.68
Organism:Homo sapiens (Human)
Description:Leukotriene B4 R1 LTB4R HUMAN::Q15722
Residue:352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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  Blast E-value cutoff:
BDBM81519
n/a
NameBDBM81519
Synonyms:CAS_117690-79-6 | CGS 23356 | CHEMBL15766 | LY 255283
TypeSmall organic molecule
Emp. Form.C19H28N4O3
Mol. Mass.360.4506
SMILESCCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1
Structure
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