| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50282081 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159640 (CHEMBL763584) |
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| IC50 | 30±n/a nM |
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| Citation |  Babine, RE; Zhang, N; Schow, SR; Jirousek, MR; Johnson, BD; Kerwar, SS; Desai, PR; Byrn, RA; Hastings, RC; Wick, MM Structure activity studies on pseudo-symmetrical HIV-1 protease inhibitors Bioorg Med Chem Lett3:1589-1594 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50282081 |
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| n/a |
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| Name | BDBM50282081 |
|---|
| Synonyms: | (S)-2-((S)-2-{(2R,6R)-2-Benzyl-4-hydroxy-6-[(S)-1-((S)-1-methoxycarbonyl-2-phenyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-7-phenyl-heptanoylamino}-4-methyl-pentanoylamino)-3-phenyl-propionic acid methyl ester | CHEMBL290163 |
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| Type | Small organic molecule |
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| Emp. Form. | C53H68N4O9 |
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| Mol. Mass. | 905.1284 |
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| SMILES | COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)Cc1ccccc1 |
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| Structure | 
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