| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor B |
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| Ligand | BDBM50282315 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34944 (CHEMBL647787) |
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| Ki | 5.9±n/a nM |
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| Citation |  Lloyd, J; Ryono, DE; Bird, JE; Buote, J; Delaney, CL; Dejneka, T; Dickinson, KE; Moreland, S; Normandin, DE; Skwish, S; Spitzmiller, ER; Waldron, TL Quinoline-4-carboxylic acids as angiotensin II receptor antagonists Bioorg Med Chem Lett4:195-200 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor B |
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| Name: | Type-1 angiotensin II receptor B |
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| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40929.44 |
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| Organism: | RAT |
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| Description: | Angiotensin II AT1B 0 RAT::P29089 |
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| Residue: | 359 |
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| Sequence: | MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
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| BDBM50282315 |
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| n/a |
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| Name | BDBM50282315 |
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| Synonyms: | 2-Ethyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-yloxy]-quinoline-4-carboxylic acid | CHEMBL57907 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H19N5O3 |
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| Mol. Mass. | 437.4501 |
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| SMILES | CCc1nc2ccccc2c(C(O)=O)c1Oc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |
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| Structure | 
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