| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C alpha type |
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| Ligand | BDBM50282658 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_160260 (CHEMBL767021) |
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| Ki | 1470±n/a nM |
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| Citation |  Lee, J; Sharma, R; Teng, K; Lewin, NE; Blumberg, PM; Marquez, VE Conformationally constrained analogues of dag .8. Changes in PK-C binding affinity produced by isosteric groups of the 3-O-acyl function in 2-deoxy-L-ribonolactones Bioorg Med Chem Lett4:1369-1374 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C alpha type |
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| Name: | Protein kinase C alpha type |
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| Synonyms: | KPCA_RAT | Pkca | Prkca | Protein kinase C (PKC) | Protein kinase C alpha | Protein kinase C alpha type |
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| Type: | Protein |
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| Mol. Mass.: | 76797.67 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P05696 |
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| Residue: | 672 |
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| Sequence: | MADVYPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN
PQFVHPILQSAV
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| BDBM50282658 |
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| n/a |
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| Name | BDBM50282658 |
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| Synonyms: | ((2R,3R)-2-Hydroxymethyl-5-oxo-tetrahydro-furan-3-yl)-acetic acid tetradecyl ester | CHEMBL28837 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H38O5 |
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| Mol. Mass. | 370.5234 |
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| SMILES | CCCCCCCCCCCCCCOC(=O)C[C@@H]1CC(=O)O[C@H]1CO |
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| Structure | 
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