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TargetGag-Pol polyprotein [489-587]
LigandBDBM50282663
Substrate/Competitorn/a
Meas. Tech.ChEBML_159322
IC50 3.4±n/a nM
Citation Kaldor, SWHammond, MDressman, BAFritz, JECrowell, TAHermann, RA New dipeptide isosteres useful for the inhibition of HIV-1 protease Bioorg Med Chem Lett4:1385-1390 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50282663
n/a
NameBDBM50282663
Synonyms:(S)-N*1*-[(1S,2R)-1-Benzyl-3-(2-tert-butylcarbamoyl-4-methyl-phenyl)-2-hydroxy-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide | CHEMBL27120 | LY-289598
TypeSmall organic molecule
Emp. Form.C36H41N5O5
Mol. Mass.623.7412
SMILESCc1ccc(C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)c2ccc3ccccc3n2)c(c1)C(=O)NC(C)(C)C
Structure
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