| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor alpha |
|---|
| Ligand | BDBM50282692 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_163473 (CHEMBL772308) |
|---|
| EC50 | 11±n/a nM |
|---|
| Citation |  Beard, RL; Gil, DW; Marler, DK; Henry, E; Colon, DF; Gillett, SJ; Arefieg, T; Breen, TS; Krauss, H; Davies, PJ; Chandraratna, RA Structural basis for the differential RXR & RAR activity of stilbene retinoid analogs Bioorg Med Chem Lett4:1447-1452 (1994) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor alpha |
|---|
| Name: | Retinoic acid receptor alpha |
|---|
| Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50778.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1466191 |
|---|
| Residue: | 462 |
|---|
| Sequence: | MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPAT
IETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYTL
TPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTV
EFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALK
VYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGL
DTLSGQPGGGGRDGGGLAPPPGSCSPSLSPSSNRSSPATHSP
|
|
|
|---|
| BDBM50282692 |
|---|
| n/a |
|---|
| Name | BDBM50282692 |
|---|
| Synonyms: | 4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid | 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid | CHEMBL12585 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26O2 |
|---|
| Mol. Mass. | 334.4513 |
|---|
| SMILES | CC1(C)CCC(C)(C)c2cc(\C=C\c3ccc(cc3)C(O)=O)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
