Reaction Details | |||
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Target | Retinoic acid receptor gamma | ||
Ligand | BDBM50032219 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_163481 (CHEMBL772394) | ||
EC50 | 2.4±n/a nM | ||
Citation | Beard, RL; Gil, DW; Marler, DK; Henry, E; Colon, DF; Gillett, SJ; Arefieg, T; Breen, TS; Krauss, H; Davies, PJ; Chandraratna, RA Structural basis for the differential RXR & RAR activity of stilbene retinoid analogs Bioorg Med Chem Lett4:1447-1452 (1994) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Retinoic acid receptor gamma | |||
Name: | Retinoic acid receptor gamma | ||
Synonyms: | NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor | ||
Type: | PROTEIN | ||
Mol. Mass.: | 50345.43 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1458016 | ||
Residue: | 454 | ||
Sequence: |
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BDBM50032219 | |||
n/a | |||
Name | BDBM50032219 | ||
Synonyms: | (E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid | 4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid | 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID | 4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid | 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | CHEMBL275311 | US9963439, TTNPB | ||
Type | Small organic molecule | ||
Emp. Form. | C24H28O2 | ||
Mol. Mass. | 348.4779 | ||
SMILES | C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C | ||
Structure |