| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
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| Ligand | BDBM50282694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_163477 (CHEMBL772312) |
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| EC50 | 21±n/a nM |
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| Citation |  Beard, RL; Gil, DW; Marler, DK; Henry, E; Colon, DF; Gillett, SJ; Arefieg, T; Breen, TS; Krauss, H; Davies, PJ; Chandraratna, RA Structural basis for the differential RXR & RAR activity of stilbene retinoid analogs Bioorg Med Chem Lett4:1447-1452 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor beta |
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| Name: | Retinoic acid receptor beta |
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| Synonyms: | HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50498.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458015 |
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| Residue: | 455 |
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| Sequence: | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
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| BDBM50282694 |
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| n/a |
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| Name | BDBM50282694 |
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| Synonyms: | 4-[(E)-2-(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | CHEMBL284167 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27BrO2 |
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| Mol. Mass. | 427.374 |
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| SMILES | C\C(=C/c1ccc(cc1)C(O)=O)c1cc2c(cc1Br)C(C)(C)CCC2(C)C |
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| Structure | 
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