| Reaction Details |
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 | Report a problem with these data |
| Target | Proprotein convertase subtilisin/kexin type 9 |
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| Ligand | BDBM50280216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_206131 |
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| Ki | 1000±n/a nM |
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| Citation |  Steiner, SJ; Bien, JT; Smith, BD Diphenylborinic acid is a strong inhibitor of serine proteases Bioorg Med Chem Lett4:2417-2420 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proprotein convertase subtilisin/kexin type 9 |
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| Name: | Proprotein convertase subtilisin/kexin type 9 |
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| Synonyms: | NARC-1 | NARC1 | Neural apoptosis-regulated convertase 1 | PC9 | PCSK9 | PCSK9_HUMAN | Proprotein convertase 9 | Proprotein convertase subtilisin/kexin type 9 | Proprotein convertase subtilisin/kexin type 9 (PCSK9) | Subtilisin/kexin type 9 | Subtilisin/kexin-like protease PC9 |
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| Type: | Enzyme |
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| Mol. Mass.: | 74286.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8NBP7 |
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| Residue: | 692 |
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| Sequence: | MGTVSSRRSWWPLPLLLLLLLLLGPAGARAQEDEDGDYEELVLALRSEEDGLAEAPEHGT
TATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTKILHVFHGLLP
GFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPPRYRADEYQPPDGGSLV
EVYLLDTSIQSDHREIEGRVMVTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAG
VAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAA
CQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVD
LFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSA
KDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAVARCAPD
EELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAP
PAEASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASC
CHAPGLECKVKEHGIPAPQEQVTVACEEGWTLTGCSALPGTSHVLGAYAVDNTCVVRSRD
VSTTGSTSEGAVTAVAICCRSRHLAQASQELQ
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| BDBM50280216 |
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| n/a |
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| Name | BDBM50280216 |
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| Synonyms: | Borinic acid derivative | CHEMBL31523 | Phenyl butyl borinic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15BO |
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| Mol. Mass. | 162.037 |
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| SMILES | CCCCB(O)c1ccccc1 |
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| Structure | 
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