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TargetGag-Pol polyprotein [489-587]
LigandBDBM50283732
Substrate/Competitorn/a
Meas. Tech.ChEBML_79815
IC50 0.030000±n/a nM
Citation Dorsey, BDMcDaniel, SLLevin, RBVacca, JPDarke, PLZuga, JAEmini, EASchleif, WALin, JHChen, IWHolloway, MKAnderson, PSHuff, JR Synthesis and evaluation of pyridyl analogs of L-735,524: Potent HIV-1 protease inhibitors Bioorg Med Chem Lett4:2769-2774 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50283732
n/a
NameBDBM50283732
Synonyms:(S)-1-[(2S,4R)-2-Hydroxy-4-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-5-pyridin-3-yl-pentyl]-4-(quinoline-8-sulfonyl)-piperazine-2-carboxylic acid tert-butylamide | CHEMBL96352
TypeSmall organic molecule
Emp. Form.C38H46N6O6S
Mol. Mass.714.873
SMILESCC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@@H](O)C[C@@H](Cc1cccnc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)S(=O)(=O)c1cccc2cccnc12
Structure
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