| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50283826 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_40039 |
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| IC50 | 1.8±n/a nM |
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| Citation |  Lowe, JA; Qian, W; Scott, PJ; McLean, S; Bryce, DK; Crawford, RT; Bordner, J 5,7-Diphenyl-3-ureidohexahydroazepin-2-ones as Cholecystokinin-B receptor ligands Bioorg Med Chem Lett4:2877-2882 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor |
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| Type: | n/a |
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| Mol. Mass.: | 48229.77 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 430 |
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| Sequence: | MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRS
SSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLL
SYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSY
SHMSTSAPPP
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| BDBM50283826 |
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| n/a |
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| Name | BDBM50283826 |
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| Synonyms: | CHEMBL327496 | N-tert-Butyl-2-{(3R,5S,7R)-3-[3-(3-fluoro-phenyl)-ureido]-2-oxo-7-phenyl-5-o-tolyl-azepan-1-yl}-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C32H37FN4O3 |
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| Mol. Mass. | 544.6596 |
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| SMILES | Cc1ccccc1[C@H]1C[C@@H](NC(=O)Nc2cccc(F)c2)C(=O)N(CC(=O)NC(C)(C)C)[C@H](C1)c1ccccc1 |
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| Structure | 
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