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TargetGag-Pol polyprotein [489-587]
LigandBDBM383
Substrate/Competitorn/a
Meas. Tech.ChEMBL_79807 (CHEMBL696067)
IC50 0.06±n/a nM
Citation Vacca, JPFitzgerald, PMHolloway, MKHungate, RWStarbuck, KEChen, LJDarke, PLAnderson, PSHuff, JR Conformationally constrained HIV-1 protease inhibitors Bioorg Med Chem Lett4:499-504 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM383
n/a
NameBDBM383
Synonyms:(3S)-oxolan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}-1-phenylpentan-2-yl]carbamate | Urethane deriv. 2
TypeSmall organic molecule
Emp. Form.C33H38N2O6
Mol. Mass.558.6646
SMILESO[C@@H](C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1 |r|
Structure
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