BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGag-Pol polyprotein [489-587]
LigandBDBM50284036
Substrate/Competitorn/a
Meas. Tech.ChEMBL_79809 (CHEMBL696069)
IC50 40±n/a nM
Citation Babine, REZhang, NSchow, SRXu, ZByrn, RAHastings, RCSemmelhack, MFWick, MMKerwar, SS Design, structure activity and x-ray crystallographic studies of pseudosymmetrical nonpeptidyl HIV-1 protease inhibitors Bioorg Med Chem Lett4:583-588 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50284036
n/a
NameBDBM50284036
Synonyms:(2R,6R)-2,6-Dibenzyl-4-hydroxy-heptanedioic acid bis-({(1S,2S)-2-[(quinoline-2-carbonyl)-amino]-cyclohexyl}-amide) | CHEMBL345868
TypeSmall organic molecule
Emp. Form.C53H58N6O5
Mol. Mass.859.0648
SMILESOC(C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCC[C@@H]1NC(=O)c1ccc2ccccc2n1)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCC[C@@H]1NC(=O)c1ccc2ccccc2n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: