Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50284036 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_79809 (CHEMBL696069) |
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IC50 | 40±n/a nM |
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Citation | Babine, RE; Zhang, N; Schow, SR; Xu, Z; Byrn, RA; Hastings, RC; Semmelhack, MF; Wick, MM; Kerwar, SS Design, structure activity and x-ray crystallographic studies of pseudosymmetrical nonpeptidyl HIV-1 protease inhibitors Bioorg Med Chem Lett4:583-588 (1994) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50284036 |
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n/a |
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Name | BDBM50284036 |
Synonyms: | (2R,6R)-2,6-Dibenzyl-4-hydroxy-heptanedioic acid bis-({(1S,2S)-2-[(quinoline-2-carbonyl)-amino]-cyclohexyl}-amide) | CHEMBL345868 |
Type | Small organic molecule |
Emp. Form. | C53H58N6O5 |
Mol. Mass. | 859.0648 |
SMILES | OC(C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCC[C@@H]1NC(=O)c1ccc2ccccc2n1)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCC[C@@H]1NC(=O)c1ccc2ccccc2n1 |
Structure |
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