| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50403370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_192889 (CHEMBL795928) |
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| IC50 | 0.030000±n/a nM |
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| Citation |  Kleinman, EF; Fray, AH; Holt, WF; Kiron, MR; Murphy, WR; Purcell, IM; Rosati, RL CP-71,362, an unusually potent inhibitor of rat and dog renin Bioorg Med Chem Lett4:589-592 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | Angiotensinogenase | REN | RENI_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 45058.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 406 |
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| Sequence: | MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEW
SQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRL
YTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEM
PALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGG
QIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISG
STSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK
LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
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| BDBM50403370 |
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| n/a |
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| Name | BDBM50403370 |
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| Synonyms: | CHEMBL2052021 | CP-71362 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H76N8O9 |
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| Mol. Mass. | 945.1973 |
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| SMILES | CC(C)C[C@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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