| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
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| Ligand | BDBM50213060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_99648 (CHEMBL709306) |
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| IC50 | <0.100000±n/a nM |
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| Citation |  Djuric', SW; Docter, SH; Yu, SS; Tsai, BS; Anglin, CP; Gaginella, TS; Kachur, JF; Keith, RH; Maziasz, TJ; Villani-Price, D; Rao, TS; Walsh, RE; Widomski, DL; Fretland, DJ Synthesis and pharmacological activity of SC-53228, a leukotriene B4 receptor antagonist with high intrinsic potency and selectivity Bioorg Med Chem Lett4:811-816 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1 |
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| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50213060 |
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| n/a |
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| Name | BDBM50213060 |
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| Synonyms: | CHEMBL355401 | SC-50135 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H41NO7 |
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| Mol. Mass. | 539.6597 |
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| SMILES | CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(=O)N2CCCC2)c1OC |
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| Structure | 
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