| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50284681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_99992 |
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| Ki | 6800±n/a nM |
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| Citation |  Andrews, EG; Antognoli, GW; Breslow, R; Carta, MP; Carty, TJ; Chambers, RJ; Cheng, JB; Cohan, VL; Collins, JL; Damon, DB; Delehunt, J; Eggler, JF; Eskra, JD; Freiert, KW; Hada, WA; Marfat, A; Masamune, H; Melvin, LS; Mularski, CJ; Naclerio, BA Synthesis and pharmacological profile of two novel heterocyclic chromanols, CP-80,798 and CP-85,958, as potent LTD4 receptor antagonists Bioorg Med Chem Lett5:1365-1370 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39007.58 |
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| Organism: | GUINEA PIG |
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| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
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| Residue: | 340 |
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| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
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| BDBM50284681 |
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| n/a |
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| Name | BDBM50284681 |
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| Synonyms: | 2-Butyl-7-(quinolin-2-ylmethoxy)-1,2,3,4-tetrahydro-naphthalen-1-ol | CHEMBL28797 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27NO2 |
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| Mol. Mass. | 361.4767 |
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| SMILES | CCCCC1CCc2ccc(OCc3ccc4ccccc4n3)cc2C1O |
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| Structure | 
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