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Reaction Details
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TargetPlatelet-activating factor receptor
LigandBDBM50284691
Substrate/Competitorn/a
Meas. Tech.ChEBML_155153
Ki 29±n/a nM
Citation Marfat, AChambers, RCheng, JCooper, KDamon, DDelehunt, JEggler, JMasamune, HMelvin, LWatson, J The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists. Bioorg Med Chem Lett5:1377-1382 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Platelet-activating factor receptor
Name:Platelet-activating factor receptor
Synonyms:PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50284691
n/a
NameBDBM50284691
Synonyms:2-(2-{3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-yl)-phenoxymethyl]-phenyl}-vinyl)-quinoline | CHEMBL28595 | CP-95492
TypeSmall organic molecule
Emp. Form.C31H24N4O
Mol. Mass.468.5485
SMILESCc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccccc4n3)c2)cc1
Structure
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