| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50284753 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105051 |
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| Ki | 5±n/a nM |
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| Citation |  Castelhano, AL; Billedeau, R; Dewdney, N; Donnelly, S; Horne, S; Kurz, LJ; Liak, TJ; Martin, R; Uppington, R; Yuan, Z; Krantz, A Novel indolactam-based inhibitors of matrix metalloproteinases Bioorg Med Chem Lett5:1415-1420 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50284753 |
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| n/a |
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| Name | BDBM50284753 |
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| Synonyms: | (R)-N*1*-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-ethyl]-N*4*-hydroxy-2-isobutyl-succinamide | CHEMBL285418 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H38N4O4 |
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| Mol. Mass. | 458.5936 |
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| SMILES | CCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO |
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| Structure | 
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