| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrilysin |
|---|
| Ligand | BDBM50284752 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_105051 |
|---|
| Ki | 1420±n/a nM |
|---|
| Citation |  Castelhano, AL; Billedeau, R; Dewdney, N; Donnelly, S; Horne, S; Kurz, LJ; Liak, TJ; Martin, R; Uppington, R; Yuan, Z; Krantz, A Novel indolactam-based inhibitors of matrix metalloproteinases Bioorg Med Chem Lett5:1415-1420 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrilysin |
|---|
| Name: | Matrilysin |
|---|
| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29681.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P09237 |
|---|
| Residue: | 267 |
|---|
| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
|
|
|
|---|
| BDBM50284752 |
|---|
| n/a |
|---|
| Name | BDBM50284752 |
|---|
| Synonyms: | CHEMBL31164 | {(S)-2-[(S)-1-Hexylcarbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-methyl-pentyl}-(quinolin-2-ylsulfanylmethyl)-phosphinic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H45N4O4PS |
|---|
| Mol. Mass. | 636.784 |
|---|
| SMILES | CCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CP(O)(=O)CSc1ccc2ccccc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
