Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50284991 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_79474 |
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Ki | 75±n/a nM |
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Citation | Park, C; Koh, JS; Son, YC; Choi, Hi; Lee, CS; Choy, N; Moon, KY; Jung, WH; Kim, SC; Yoon, H Rational design of irreversible, pseudo-C2-symmetric hiv-1 protease inhibitors Bioorg Med Chem Lett5:1843-1848 (1995) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50284991 |
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n/a |
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Name | BDBM50284991 |
Synonyms: | CHEMBL295499 | [(S)-1-((S)-1-{3-[(S)-1-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-2-phenyl-ethyl]-oxiranyl}-2-phenyl-ethylcarbamoyl)-2-methyl-propyl]-carbamic acid benzyl ester |
Type | Small organic molecule |
Emp. Form. | C44H52N4O7 |
Mol. Mass. | 748.9063 |
SMILES | CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C1OC1[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C |
Structure |
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