Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50009242 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_79474 (CHEMBL691404) |
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Ki | <1±n/a nM |
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Citation | Park, C; Koh, JS; Son, YC; Choi, Hi; Lee, CS; Choy, N; Moon, KY; Jung, WH; Kim, SC; Yoon, H Rational design of irreversible, pseudo-C2-symmetric hiv-1 protease inhibitors Bioorg Med Chem Lett5:1843-1848 (1995) Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50009242 |
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n/a |
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Name | BDBM50009242 |
Synonyms: | CHEMBL48565 | {(S)-1-[(1S,2S,3R,4S)-1-Benzyl-4-((S)-2-benzyloxycarbonylamino-3-methyl-butyrylamino)-2,3-dihydroxy-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester | {1-[1-Benzyl-4-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-2,3-dihydroxy-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester |
Type | Small organic molecule |
Emp. Form. | C44H54N4O8 |
Mol. Mass. | 766.9216 |
SMILES | CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C |
Structure |
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