| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsin-like elastase family member 2A |
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| Ligand | BDBM50285107 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154797 (CHEMBL761676) |
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| IC50 | 490±n/a nM |
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| Citation |  Boschetti, CE; Mata, EG; Mascaretti, OA; Cricco, JA; Coux, G; Roveri, OA Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones Bioorg Med Chem Lett5:2033-2036 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsin-like elastase family member 2A |
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| Name: | Chymotrypsin-like elastase family member 2A |
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| Synonyms: | CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28705.23 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_156951 |
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| Residue: | 269 |
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| Sequence: | MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGG
TLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGN
DIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLV
VDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSS
LGCNYYHKPSVFTRVSNYIDWINSVIANN
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| BDBM50285107 |
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| n/a |
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| Name | BDBM50285107 |
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| Synonyms: | (2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-sulfonyloxy)-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester | CHEMBL418507 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27NO10S2 |
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| Mol. Mass. | 517.57 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)O[C@@H]1[C@@H]2N([C@@H](C(=O)OCOC(=O)C(C)(C)C)C(C)(C)S2(=O)=O)C1=O |
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| Structure | 
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