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TargetChymotrypsin-like elastase family member 2A
LigandBDBM50285111
Substrate/Competitorn/a
Meas. Tech.ChEBML_154799
IC50 130±n/a nM
Citation Boschetti, CEMata, EGMascaretti, OACricco, JACoux, GRoveri, OA Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones Bioorg Med Chem Lett5:2033-2036 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Chymotrypsin-like elastase family member 2A
Name:Chymotrypsin-like elastase family member 2A
Synonyms:CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:PROTEIN
Mol. Mass.:28705.23
Organism:Sus scrofa
Description:ChEMBL_156951
Residue:269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGG
TLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGN
DIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLV
VDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSS
LGCNYYHKPSVFTRVSNYIDWINSVIANN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50285111
n/a
NameBDBM50285111
Synonyms:(2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester | CHEMBL292476
TypeSmall organic molecule
Emp. Form.C16H19NO8S2
Mol. Mass.417.454
SMILESCC1(C)[C@@H](N2[C@@H]([C@@H](OS(C)(=O)=O)C2=O)S1(=O)=O)C(=O)OCc1ccccc1
Structure
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