| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase 1 |
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| Ligand | BDBM50285120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_40230 (CHEMBL654129) |
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| IC50 | >3000000±n/a nM |
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| Citation |  Danelon, GO; Mata, EG; Mascaretti, OA; Girardini, J; Marro, M; Roveri, OA Synthesis and β-lactamase inhibitory evaluation of novel 6α-halo-2β-chloromethyl-2α-methylpenam-3α-carboxylic acids and their sulfones and 6α-halo-2β-mercaptobenzothiazolylmethyl-2α-methylpenam-3α-carboxylic acids Bioorg Med Chem Lett5:2037-2040 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase 1 |
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| Name: | Beta-lactamase 1 |
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| Synonyms: | BLAC_BACCE | blaY |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33326.66 |
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| Organism: | Bacillus cereus |
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| Description: | ChEMBL_40230 |
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| Residue: | 306 |
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| Sequence: | MILKNKRMLKIGICVGILGLSITSLEAFTGESLQVEAKEKTGQVKHKNQATHKEFSQLEK
KFDARLGVYAIDTGTNQTISYRPNERFAFASTYKALAAGVLLQQNSIDSLNEVITYTKED
LVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRHMGDRITM
SNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRKILTEWMKGNATGDKLI
RAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNSAPIIVLISSKDEKEAIYNDQLIAEATK
VIVKGS
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| BDBM50285120 |
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| n/a |
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| Name | BDBM50285120 |
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| Synonyms: | (2S,3R,5R,6S)-3-Chloromethyl-6-fluoro-3-methyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL64818 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9ClFNO5S |
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| Mol. Mass. | 285.677 |
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| SMILES | C[C@]1(CCl)[C@@H](N2[C@@H]([C@@H](F)C2=O)S1(=O)=O)C(O)=O |
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| Structure | 
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