| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50285523 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1651 |
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| EC50 | 14±n/a nM |
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| Citation |  Macor, JE; Blank, DH; Desai, K; Fox, CB; Koe, BK; Lebel, LA; Post, RJ; Schmidt, AW; Schulz, DW; Seymour, PA 5-cyano-1-[3-(N-methylpyrrolidin-2R-ylmethyl)indol-5-yl] benzimidazole (CP-161,242): A potent, centrally active 5-HT1D receptor agonist and benzodiazepine partial agonist Bioorg Med Chem Lett5:2391-2396 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41780.38 |
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| Organism: | GUINEA PIG |
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| Description: | 5-HT1D HTR1D GUINEA PIG::Q60484 |
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| Residue: | 376 |
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| Sequence: | MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQ
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFT
TAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATK
TLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNE
DFRQAFQKVVHFRKAS
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| BDBM50285523 |
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| n/a |
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| Name | BDBM50285523 |
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| Synonyms: | CHEMBL80189 | [2-(5-Imidazo[4,5-b]pyridin-3-yl-1H-indol-3-yl)-ethyl]-dimethyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N5 |
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| Mol. Mass. | 305.377 |
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| SMILES | CN(C)CCc1c[nH]c2ccc(cc12)-n1cnc2cccnc12 |
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| Structure | 
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