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TargetGag-Pol polyprotein [489-587]
LigandBDBM50285701
Substrate/Competitorn/a
Meas. Tech.ChEMBL_79978 (CHEMBL874137)
Ki 0.070±n/a nM
Citation Randad, RSLubkowska, LBujacz, ANaik, RHGulnik, SVYu, BSilva, AMunshi, SLynch, TMClanton, DJBhat, TNErickson, JW Structure-based design of achiral anthranilamides as P2/P2′ surrogates for symmetry-based HIV protease inhibitors: design, synthesis, X-ray structure, enzyme inhibition and antiviral activity Bioorg Med Chem Lett5:2557-2562 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50285701
n/a
NameBDBM50285701
Synonyms:Anthranilamide derivative | CHEMBL313767
TypeSmall organic molecule
Emp. Form.C46H44N6O7
Mol. Mass.792.8776
SMILESO[C@@H](C[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1)[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1
Structure
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