| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-gamma |
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| Ligand | BDBM50285920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_197215 |
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| EC50 | 160±n/a nM |
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| Citation |  Beard, RL; Colon, DF; Klein, ES; Vorse, KA; Chandraratna, RA Differential RXR & RAR activity of stilbene retinoid analogs bearing thiazole and imidazole carboxylic acids Bioorg Med Chem Lett5:2729-2734 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-gamma |
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| Name: | Retinoic acid receptor RXR-gamma |
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| Synonyms: | NR2B3 | Nuclear receptor subfamily 2 group B member 3 | RXRG | RXRG_HUMAN | Retinoic acid receptor RXR-gamma | Retinoid X receptor gamma | Retinoid X receptor gamma/retinoic acid receptor alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50878.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_197216 |
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| Residue: | 463 |
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| Sequence: | MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL
EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
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| BDBM50285920 |
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| n/a |
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| Name | BDBM50285920 |
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| Synonyms: | 2-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-thiazole-5-carboxylic acid | CHEMBL93577 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25NO2S |
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| Mol. Mass. | 355.494 |
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| SMILES | C\C(=C/c1ncc(s1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C |
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| Structure | 
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