| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50121513 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_79955 |
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| IC50 | 0.300000±n/a nM |
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| Citation |  Munroe, JE; Hornback, WJ; Campbell, JB; Ouellette, MA; Hatch, SD; Muesing, MA; Wiskerchen, MA; Baxter, AJ; Su, K; Campanale, K Ly316340: A potent HIV-1 protease inhibitor containing a high affinity octahydrothienopyridine hydroxyethylamine isostere Bioorg Med Chem Lett5:2885-2890 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50121513 |
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| n/a |
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| Name | BDBM50121513 |
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| Synonyms: | (3aR,6S,7aS)-5-[(2R,3R)-2-Hydroxy-3-(3-hydroxy-2-methyl-benzoylamino)-4-phenylsulfanyl-butyl]-octahydro-thieno[3,2-c]pyridine-6-carboxylic acid tert-butylamide | CHEMBL98710 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H41N3O4S2 |
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| Mol. Mass. | 571.794 |
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| SMILES | Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCS[C@H]2C[C@H]1C(=O)NC(C)(C)C |
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| Structure | 
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