| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50286013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_155163 (CHEMBL761901) |
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| Ki | 68±n/a nM |
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| Citation |  Davidsen, SK; Summers, JB; Sweeny, DJ; Holms, JH; Albert, DH; Carrera, GM; Tapang, P; Magoc, TJ; Conway, RG; Rhein, DA Synthesis of active metabolites of indole pyrrolothiazole paf antagonists Bioorg Med Chem Lett5:2909-2912 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PTAFR_RAT | Platelet activating factor receptor | Platelet-activating factor receptor | Ptafr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39221.53 |
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| Organism: | RAT |
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| Description: | PAF Platelet activating factor PTAFR RAT::P46002 |
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| Residue: | 341 |
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| Sequence: | MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLT
VADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVA
YPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPY
SVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAV
FVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFR
KHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN
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| BDBM50286013 |
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| n/a |
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| Name | BDBM50286013 |
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| Synonyms: | (cis)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-1H-indole-3-carbonyl]-2-hydroxy-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-2-ium | (trans)-(2S,3R)-7-[1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-1H-indole-3-carbonyl]-2-hydroxy-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazol-2-ium | CHEMBL538366 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H23FN4O3S |
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| Mol. Mass. | 526.581 |
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| SMILES | CN(C)C(=O)n1cc(C(=O)c2ccn3[C@@H](c4cccnc4)S(=O)Cc23)c2ccc(cc12)-c1ccc(F)cc1 |r| |
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| Structure | 
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