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Reaction Details
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TargetPTAFR
LigandBDBM50035397
Substrate/Competitorn/a
Meas. Tech.ChEMBL_155162
Ki 3.8±n/a nM
Citation Davidsen SKSummers JBSweeny DJHolms JHAlbert DHCarrera GMTapang PMagoc TJConway RGRhein DA Synthesis of active metabolites of indole pyrrolothiazole paf antagonists Bioorg Med Chem Lett 5:2909-2912 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
PTAFR
Name:Platelet activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39221.53
Organism:RAT
Description:PAF Platelet activating factor PTAFR RAT::P46002
Residue:341
Sequence:
MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLT
VADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVA
YPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPY
SVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAV
FVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFR
KHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50035397
n/a
NameBDBM50035397
Synonyms:6-(4-Fluoro-phenyl)-3-((R)-3-pyridin-3-yl-1H-pyrrolo[1,2-c]thiazole-7-carbonyl)-indole-1-carboxylic acid dimethylamide | CHEMBL98318
TypeSmall organic molecule
Emp. Form.C29H23FN4O2S
Mol. Mass.510.582
SMILESCN(C)C(=O)n1cc(C(=O)c2ccn3[C@H](SCc23)c2cccnc2)c2ccc(cc12)-c1ccc(F)cc1
Structure
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