| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM150 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157866 |
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| Ki | 0.310000±n/a nM |
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| Citation |  Wilkerson, WW; Hollis, AY; Cheatham, WW; Lam, GN; Erickson-Viitanen, S; Bacheler, L; Cordova, BC; Klabe, RM; Meek, JL A bis-[N-3-(1-hydroxy-1-methyl-ethyl)-benzyl)-cyclic urea as a HIV protease inhibitor Bioorg Med Chem Lett5:3027-3032 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM150 |
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| n/a |
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| Name | BDBM150 |
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| Synonyms: | (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({[4-(hydroxymethyl)phenyl]methyl})-1,3-diazepan-2-one | DMP323 |
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| Type | n/a |
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| Emp. Form. | C35H38N2O5 |
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| Mol. Mass. | 566.6866 |
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| SMILES | OCc1ccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3ccc(CO)cc3)C2=O)cc1 |
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| Structure | 
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