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TargetPlatelet-activating factor receptor
LigandBDBM50286203
Substrate/Competitorn/a
Meas. Tech.ChEBML_164930
IC50 3±n/a nM
Citation Cooper, KFray, MJParry, MJRichardson, KSteele, J Enantiodifferentiation of dihydropyridine PAF antagonists Bioorg Med Chem Lett5:3085-3090 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Platelet-activating factor receptor
Name:Platelet-activating factor receptor
Synonyms:PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:39219.60
Organism:Homo sapiens (Human)
Description:PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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  Blast E-value cutoff:
BDBM50286203
n/a
NameBDBM50286203
Synonyms:4-(2-Chloro-phenyl)-6-methyl-2-[2-(2-methyl-benzoimidazol-1-yl)-ethoxymethyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester | CHEMBL104290
TypeSmall organic molecule
Emp. Form.C32H32ClN5O4
Mol. Mass.586.081
SMILESCCOC(=O)C1=C(COCCn2c(C)nc3ccccc23)N=C(C)C(C1c1ccccc1Cl)C(=O)Nc1ccccn1 |c:5,t:23|
Structure
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