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TargetMatrix metalloproteinase-1 (MMP1)
LigandBDBM50286340
Substrate/Competitorn/a
Meas. Tech.ChEBML_49511
Ki 2±n/a nM
Citation Singh JConzentino PCundy KGainor JAGilliam CLGordon TDJohnson JAMorgan BASchneider EDWahl RCWhipple DA Relationship between structure and bioavailability in a series of hydroxamate based metalloprotease inhibitors Bioorg Med Chem Lett 5:337-342 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase-1 (MMP1)
Name:Matrix metalloproteinase (1 and 13)
Synonyms:Fibroblast collagenase | Interstitial collagenase | MMP1 | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1)
Type:Enzyme
Mol. Mass.:54010.26
Organism:Homo sapiens (Human)
Description:
Residue:469
Sequence:
MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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  Blast E-value cutoff:
BDBM50286340
n/a
NameBDBM50286340
Synonyms:(R)-N*1*-[(S)-1-(4-Benzyloxy-butylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-N*4*-hydroxy-2-isobutyl-succinamide | CHEMBL114094
TypeSmall organic molecule
Emp. Form.C30H40N4O5
Mol. Mass.536.6624
SMILESCC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCOCc1ccccc1
Structure
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