Reaction Details | |||
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Target | Retinoic acid receptor alpha | ||
Ligand | BDBM50032219 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_195193 (CHEMBL802229) | ||
EC50 | 21±n/a nM | ||
Citation | Chandraratna, RA; Gillett, SJ; Song, TK; Attard, J; Vuligonda, S; Garst, ME; Arefieg, T; Gil, DW; Wheeler, L Synthesis and pharmacological activity of conformationally restricted, acetylenic retinoid analogs Bioorg Med Chem Lett5:523-527 (1995) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Retinoic acid receptor alpha | |||
Name: | Retinoic acid receptor alpha | ||
Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic acid receptor alpha | Retinoic acid receptor alpha/Retinoid X receptor alpha | Retinoid X receptor gamma/retinoic acid receptor alpha | Retinoid receptor | ||
Type: | PROTEIN | ||
Mol. Mass.: | 50778.87 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1466191 | ||
Residue: | 462 | ||
Sequence: |
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BDBM50032219 | |||
n/a | |||
Name | BDBM50032219 | ||
Synonyms: | (E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid | 4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid | 4-[(1E)-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PROP-1-ENYL]BENZOIC ACID | 4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid | 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid | CHEMBL275311 | US9963439, TTNPB | ||
Type | Small organic molecule | ||
Emp. Form. | C24H28O2 | ||
Mol. Mass. | 348.4779 | ||
SMILES | C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C | ||
Structure |