| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50033447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_2037 |
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| Ki | 0.870000±n/a nM |
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| Citation |  Perez, M; Pauwels, P; Palmier, C; John, GW; Valentin, JP; Halazy, S 5-O-Carboxymethyl piperazide derivatives of serotonin: a new class of potent and selective 5-HT1D receptor agonists Bioorg Med Chem Lett5:663-666 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41920.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. |
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| Residue: | 377 |
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| Sequence: | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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| BDBM50033447 |
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| n/a |
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| Name | BDBM50033447 |
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| Synonyms: | 2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-tolyl-piperazin-1-yl)-ethanone | CHEMBL120055 | CHEMBL321818 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N4O2 |
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| Mol. Mass. | 392.494 |
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| SMILES | Cc1ccccc1N1CCN(CC1)C(=O)COc1ccc2[nH]cc(CCN)c2c1 |
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| Structure | 
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