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TargetGag-Pol polyprotein [489-587]
LigandBDBM50286700
Substrate/Competitorn/a
Meas. Tech.ChEBML_157737
Ki 265±n/a nM
Citation Kalish, VJTatlock, JHDavies, JFKaldor, SWDressman, BAReich, SPino, MNyugen, DAppelt, KMusick, LWu, Bw Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitors Bioorg Med Chem Lett5:727-732 (1995)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50286700
n/a
NameBDBM50286700
Synonyms:CHEMBL162866 | Quinoline-4-carboxylic acid [(1R,2R)-3-(2-tert-butylcarbamoyl-phenyl)-2-hydroxy-1-(naphthalen-2-ylsulfanylmethyl)-propyl]-amide
TypeSmall organic molecule
Emp. Form.C35H35N3O3S
Mol. Mass.577.736
SMILESCC(C)(C)NC(=O)c1ccccc1C[C@@H](O)[C@H](CSc1ccc2ccccc2c1)NC(=O)c1ccnc2ccccc12
Structure
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