Ki Summary

Reaction Details

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Target

Bile salt-activated lipase

Ligand

BDBM50286879

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_154778 (CHEMBL761498)

30000±n/a nM

Citation

Lin, G; Liu, HC; Tsai, YC Atropisomeric carbamoyl type inhibitors of pancreatic cholesterol esterase Bioorg Med Chem Lett6:43-46 (1996) Article

More Info.:

Get all data from this article, Assay Method

Bile salt-activated lipase

Name:

Bile salt-activated lipase

Synonyms:

CEL | CEL_BOVIN | Cholesterol esterase

Type:

PROTEIN

Mol. Mass.:

65152.77

Organism:

Bos taurus

Description:

ChEMBL_154778

Residue:

597

Sequence:

LGASRLGPSPGCLAVASAAKLGSVYTEGGFVEGVNKKLSLFGDSIDIFKGIPFAAAPKAL
EKPERHPGWQGTLKAKSFKKRCLQATLTQDSTYGNEDCLYLNIWVPQGRKEVSHDLPVMI
WIYGGAFLMGASQGANFLSNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDSNLPGNY
GLWDQHMAIAWVKRNIEAFGGDPDNITLFGESAGGASVSLQTLSPYNKGLIKRAISQSGV
GLCPWAIQQDPLFWAKRIAEKVGCPVDDTSKMAGCLKITDPRALTLAYKLPLGSTEYPKL
HYLSFVPVIDGDFIPDDPVNLYANAADVDYIAGTNDMDGHLFVGMDVPAINSNKQDVTEE
DFYKLVSGLTVTKGLRGANATYEVYTEPWAQDSSQETRKKTMVDLETDILFLIPTKIAVA
QHKSHAKSANTYTYLFSQPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRAQDRTVSK
AMIAYWTNFARTGDPNTGHSTVPANWDPYTLEDDNYLEINKQMDSNSMKLHLRTNYLQFW
TQTYQALPTVTSAGASLLPPEDNSQASPVPPADNSGAPTEPSAGDSEVAQMPVVIGF

BDBM50286879

n/a

Name

BDBM50286879

Synonyms:

Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']binaphthalenyl-2-yl ester | CHEMBL141926

Type

Small organic molecule

Emp. Form.

C30H32N2O4

Mol. Mass.

484.5861

SMILES

CCCCNC(=O)Oc1ccc2ccccc2c1-c1c(OC(=O)NCCCC)ccc2ccccc12 |(16.13,.89,;14.79,1.65,;13.46,.88,;12.12,1.65,;10.79,.86,;9.45,1.63,;9.43,3.17,;8.12,.86,;6.77,1.63,;6.77,3.17,;5.44,3.94,;4.11,3.15,;2.78,3.92,;1.45,3.15,;1.45,1.6,;2.78,.83,;4.11,1.61,;5.44,.84,;5.44,-.7,;4.11,-1.47,;2.78,-.7,;1.45,-1.47,;1.45,-3.01,;.12,-.68,;-1.23,-1.47,;-2.56,-.68,;-3.9,-1.45,;-5.23,-.68,;4.11,-3.01,;5.44,-3.78,;6.79,-3.01,;8.12,-3.78,;9.46,-3.01,;9.46,-1.47,;8.13,-.68,;6.79,-1.47,)|

Structure