| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50287178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_60231 |
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| Ki | 151±n/a nM |
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| Citation |  Glase, SA; Akunne, HC; Heffner, TG; Johnson, SJ; Kesten, SR; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wright, JL; Wise, LD 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamides: Selective dopamine D3 receptor partial agonists Bioorg Med Chem Lett6:1361-1366 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50287178 |
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| n/a |
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| Name | BDBM50287178 |
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| Synonyms: | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2-nitro-phenyl)-piperazin-1-yl]-ethyl}-amide | CHEMBL29436 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25BrN4O4 |
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| Mol. Mass. | 513.384 |
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| SMILES | COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1[N+]([O-])=O |
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| Structure | 
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