| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50287536 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_144144 |
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| Ki | 58±n/a nM |
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| Citation |  Wright, J; Bolton, G; Creswell, M; Downing, D; Georgic, L; Heffner, T; Hodges, J; MacKenzie, R; Wise, L 8-amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists Bioorg Med Chem Lett6:1809-1814 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50287536 |
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| n/a |
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| Name | BDBM50287536 |
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| Synonyms: | 6-(2-Fluoro-benzenesulfonyl)-5-nitro-quinolin-8-ylamine | CHEMBL52643 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10FN3O4S |
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| Mol. Mass. | 347.321 |
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| SMILES | Nc1cc(c([N+]([O-])=O)c2cccnc12)S(=O)(=O)c1ccccc1F |
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| Structure | 
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