| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50287799 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_37404 |
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| Ki | 1300±n/a nM |
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| Citation |  Fisher, LG; Sher, PM; Skwish, S; Michel, IM; Seiler, SM; Dickinson, KE BMS-187257, a potent, selective, and novel heterocyclic β3 adrenergic receptor agonist Bioorg Med Chem Lett6:2253-2258 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | adrenergic Beta1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51338.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08588 |
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| Residue: | 477 |
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| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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| BDBM50287799 |
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| n/a |
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| Name | BDBM50287799 |
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| Synonyms: | 4-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-propyl]-thiazol-5-yl}-butyric acid | CHEMBL72169 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26N2O4S |
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| Mol. Mass. | 378.486 |
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| SMILES | C[C@H](Cc1ncc(CCCC(O)=O)s1)NC[C@H](O)COc1ccccc1 |
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| Structure | 
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