| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-10 |
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| Ligand | BDBM50287851 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_143222 |
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| Ki | 3.1±n/a nM |
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| Citation |  Elliott, RL; Kopecka, H; Gunn, DE; Lin, NH; Garvey, DS; Ryther, KB; Holladay, MW; Anderson, DJ; Campbell, JE; Sullivan, JP; Buckley, MJ; Gunther, KL; O'Neill, AB; Decker, MW; Arnerić, SP 2-(Aryloxymethyl) azacyclic analogues as novel nicotinic acetylcholine receptor (nAChR) ligands Bioorg Med Chem Lett6:2283-2288 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor subunit alpha-10 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-10 |
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| Synonyms: | ACH10_RAT | Chrna10 | Neuronal acetylcholine receptor protein alpha-10 subunit | Nicotinic acetylcholine receptor alpha9/alpha10 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49830.54 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_143222 |
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| Residue: | 447 |
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| Sequence: | MGTRSHYLDLGFLLLLFLPAECLGAEGRLAHKLFRDLFANYTSALRPVADTDQTLNVTLE
VTLSQIIDMDERNQVLTLYLWIRQEWTDAYLHWDPKAYGDLDAIRIPSRLVWRPDIVLYN
KADTQPPASASTNVVVRHDGAVRWDAPAITRSSCRVDVSAFPFDAQRCGLTFGSWTHGGH
QLDVRPRGTSASLADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYV
CNLLLPCVFISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLILAESMPPAESVPLIGK
YYMATMTMVTFSTALTILIMNLHYCGPNAHPVPAWARVLLLGHLAKGLCVRERGEPCGQS
KPLESAPSLQPPPASPAGPCHEPRCLCHQEALLHHIASIASTFRSHRAAQRRHEDWKRLA
RVMDRFFLGIFFCMALVMSLIVLVQAL
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| BDBM50287851 |
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| n/a |
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| Name | BDBM50287851 |
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| Synonyms: | (S)-2-(3-Fluoro-phenoxymethyl)-azetidine | CHEMBL305674 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12FNO |
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| Mol. Mass. | 181.2068 |
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| SMILES | Fc1cccc(OC[C@@H]2CCN2)c1 |
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| Structure | 
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