Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM50288284 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_3403 (CHEMBL619165) | ||
Kd | 2.6±n/a nM | ||
Citation | Paulis, Td; Trivedi, BL; Zhang, ZJ; Schmidt, DE; Ebert, MH; Hewlett, WA (S)-4-amino-5-chloro-3-iodo-2-methoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide (TRIZAC), a high-affinity ligand for the 5-HT-3 receptor Bioorg Med Chem Lett6:2657-2662 (1996) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_RAT | 5ht3 | Htr3 | Htr3a | Serotonin (5-HT) receptor | Zacopride site-R | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 55428.70 | ||
Organism: | RAT | ||
Description: | 5-HT3 HTR3A RAT::P35563 | ||
Residue: | 483 | ||
Sequence: |
| ||
BDBM50288284 | |||
n/a | |||
Name | BDBM50288284 | ||
Synonyms: | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-iodo-2-methoxy-benzamide | CHEMBL421738 | ||
Type | Small organic molecule | ||
Emp. Form. | C15H20IN3O2 | ||
Mol. Mass. | 401.2427 | ||
SMILES | COc1cc(N)c(I)cc1C(=O)NC1CN2CCC1CC2 |(16.09,-14.57,;16.09,-13.02,;14.76,-12.26,;13.41,-13.02,;12.08,-12.26,;10.74,-13.02,;12.08,-10.71,;10.74,-9.94,;13.41,-9.94,;14.76,-10.71,;16.09,-9.94,;16.09,-8.4,;17.42,-10.71,;18.74,-9.94,;20.07,-10.71,;21.39,-9.95,;21.42,-8.42,;20.08,-7.64,;18.74,-8.41,;19.5,-9.73,;20.82,-8.97,)| | ||
Structure |